Do you want to make the bridge between scientific evidence and the real world?
That's what U-REACH is about: a flexible, open methodology to share scientific evidence about health with the people who need it.
Explore our open evidence platforms
| Platform | Meta-analyses | Interventions | Age groups | Open access | |
|---|---|---|---|---|---|
| InterventionsWhich interventions work, and how well | |||||
| EBIA-CTAutism | 133 | 51 | Open | ||
| EBI-ADHDADHD | 57 | 32 | Open | ||
| EBI-BDBipolar disorder | 75 | 78 | Open | ||
| EBI-PSYCHEPsychedelics | 1 | 5 | Open | ||
| EBI-SCZSoonSchizophrenia | 240 | 368 | Preview | ||
| NeuropsychologyCognitive strengths and difficulties, from case-control studies | |||||
| EBIC-ASDPreviewAutism | 50 | 45factors | Preview | ||
| PsychometricsHow well a test measures what it claims | |||||
| EBP-MASCPreviewSocial cognition (MASC) | 1 | 1test | Preview | ||
Coming next: sleep. In the pipeline: OCD, anxiety, eating disorders, intellectual disability, and dyslexia & dyscalculia. Register a U-REACH project to help build one.
The story so far
Statistical software we built for the calculations needed by the reviews.
100,000 downloadsAutism umbrella review of psychosocial therapies.
Molecular PsychiatrySoftware we built for exhaustive effect size calculations to limit data analysis error.
20,000 downloadsA methodological article defining the U-REACH framework.
BMJ Mental HealthThe umbrella review of all ADHD interventions.
BMJAutism alternative-therapies review: top-5 in general media, Sept 2025.
Nature Human BehaviourA living review of psychedelics and MDMA for mental disorders.
Eur. Neuropsychopharm.The umbrella review of all bipolar interventions.
BMJFramework and software we built to catch errors in meta-analyses.
The first U-REACH project begins, on autism.
The first version of the autism platform goes live.
A €220k grant to continue the autism project.
French research agencyCo-design of the ADHD platform begins with 1,400+ clinicians and families.
A $348k grant for a living psychedelics review.
Canadian research agencyWe collaborated on renewing France's autism and Canada's bipolar guidelines.
20+ professional and lived-experience groups endorse our ADHD platform.
Next: new work on schizophrenia, sleep, and more!
Other online evidence synthesis platforms
These projects are not U-REACH projects but they used online platforms to disseminate their results. They are presented to provide an overview of the different approaches and information contained in existing platforms.
The U-REACH method
U-REACH turns a mountain of research into a living, open platform, in four steps.
Umbrella-Review
Collect every meta-analysis on a topic and extract the data.
Evaluation
Appraise the quality of the reviews and their studies.
Assessment
Re-run the results and rate the certainty of the evidence.
Communication Hub
Share it all through an open, interactive web platform.
Run your own U-REACH project
Download the protocol checklist (inspired by PROSPERO and our own experience) and register your project in our open OSF folder.
Project Leaders
Corentin J. Gosling, PhD
Université Paris Nanterre, FR
Hôpital Robert Debré, FR
University of Southampton, UK
Samuele Cortese, MD, PhD
University of Southampton, UK
New York University, USA
University of Bari, Italy
Richard Delorme, MD, PhD
Hôpital Robert Debré, FR
Institut Pasteur, FR
Marco Solmi, MD, PhD
University of Ottawa, CA
Charité Universitätsmedizin, GE